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Literature summary extracted from

  • Shiomi, K.; Hatano, H.; Morimoto, H.; Ui, H.; Sakamoto, K.; Kita, K.; Tomoda, H.; Lee, E.W.; Heo, T.R.; Kawagishi, H.; Omura, S.
    Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum (2007), Planta Med., 73, 1478-1481.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.6 decursin
-
 Ascaris suum
1.3.1.6 decursinol
-
 Ascaris suum
1.3.1.6 decursinol angelate
-
 Ascaris suum

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.6 Ascaris suum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.6 fumarate + NADH + H+
-
 Ascaris suum succinate + NAD+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.6 NADH-fumarate reductase
-
 Ascaris suum
1.3.1.6 NFRD
-
 Ascaris suum

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.6 NADH
-
 Ascaris suum

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.3.1.6 0.0011
-
-
 Ascaris suum decursin
1.3.1.6 0.0027
-
-
 Ascaris suum decursinol angelate
1.3.1.6 0.0048
-
-
 Ascaris suum decursinol